【文獻(xiàn)標(biāo)題】Mixed heavy metals exposure affects the renal function mediated by 8-OHG: A cross-sectional study in rural residents of China 【作者】Xiaoyu Tian , Xiaobing Shan , Li Ma , et.al 【作者單位】蘭州大學(xué)（Lanzhou University） 【文獻(xiàn)中引用產(chǎn)品】 人視黃醇結(jié)合蛋白(RBP)ELISA試劑盒 人8-羥基鳥(niǎo)嘌呤（8-OHG）ELISA試劑盒 【關(guān)鍵詞】Heavy metals ,Renal function ,8-OHG ,Exposure-response relationship ,Mediation analysis 【DOI】doi.org/10.1016/j.envpol.2022.120727 【影響因子(IF)】9.98 【出版期刊】《Environmental Pollution》 【產(chǎn)品原文引用】 The following biomarkers for renal function were measured in urine: creatinine (Cr), β2-MG, NAG, RBP and 8-OHG. The concentration of Cr and NAG were measured by a creatinine assay kit (Nanjing Jiancheng Bioengineering Institute, China) and NAG kit (Nanjing Jiancheng Bioengineering Institute, China), respectively. β2-MG, RBP and 8-OHG were determined by the QuicKey Human BMG/β2-MG (Beta-2-Microglobulin) ELISA Kit (Elabscience Biotechnology Co. Ltd, China), Human RBP ELISA KIT (Shanghai Hengyuan Biological Technology Co. Ltd, China) and Human 8-OHG ELISA KIT (Shanghai Hengyuan Biological Technology Co. Ltd, China), respectively, according to the instructions of the manufacturer. The assay range of β2-MG, RBP and 8-OHG were 0.78–50 μg/L, 2–65 μg/L and 3–100 ng/L, respectively. All operation steps were strictly carried out according to the instructions of the kit.
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